Combined Immune Deficiency Disease:CIDD
Combined Immune Deficiency Disease:CIDD – On last night’s episode of “Extreme Makeover: Home Edition” on ABC the Napper family whose 12-year-old, daughter Holli, is battling Combined Immune Deficiency Disease aka CIDD took a vacation to Hawaii while Ty and the team work to rebuild their Las Vegas home.What is Combined Immune Deficiency Disease ?
Combined Immune Deficiency Disease is a life-threatening illness that provokes recurrent infections, diarrhea, dermatitis, and failure to thrive which means:
It is caused by mutations in 1 of 10 known genes. These molecular defects block the differentiation and proliferation of T cells and, in some types, of B cells and NK cells. Antibody production is impaired severely, even when mature B cells are present. NK cells, a component of innate immunity, are affected variably. Classification of the etiologies of SCID is according to the corresponding phenotypic lymphocyte profiles: T-lymphocyte (T) negative, B-lymphocyte (B) positive, natural killer cell (NK)-negative (T- B+ NK-), T- B- NK-; T- B- NK+; and T- B+ NK+.
Holli’s mother Jane said:
“It’s one of the more severe types of the 150 different Primary Immunodeficiency Diseases.” “Approximately a quarter of a million Americans are diagnosed with PIDD.”
“This diagnosis came after almost eight years of battling sinus infections, ear infections, bronchitis and severe colds.” “She’s endured numerous tests along with two sinus surgeries, insertion of ear tubes, an adenoidectomy and a tonsillectomy; all before the age of 7.” Holli was also on antibiotics for most of each month, especially in the winter”
That’s the latest update on Combined Immune Deficiency Disease:CIDD.
Category: Health



